Androids are built to be the world's perfect super soldiers in this universe, in competition with the altered humans that your character would be part of, they're built from the strongest metals, most advanced tech, and near indistinguishable from human AIs.
They come with everything from laser eyes, to jetpacks, to forcefields. And of course, at first, these guys will look completely human.
So to put it bluntly, they're few, far between, and tough as nails. A concentrated burst of machine gun fire could damage one heavily, but small arms and incendiary attacks will do very little, and melee is almost entirely out of the question, short of a sledgehammer, and even that would take a long time to do any significant damage. I have purposely made the one seen so far be very clumsy, so as not to be unfair to the players :)
But in future, expect to have to outsmart any androids you encounter, cyborgs are a little easier, due to the fleshy human bits still left, but they are going to be treated as the lowest tier of miniboss
So, for a basic scale of power
Cyborgs/Lesser Mutants (We'll get into these later on)
Mutants (Howlers are a good example)
Advanced Mutants (Again, we'll get into these later, but expect a tough fight with these bastards)
Androids (Like the Bandit Leader, but not all of them will be so clumsy)
Remnants (These will be very, very rare, and often not hostile, The Judge is a notable example)