zero problems so far, other than the fact that I gave mac a "much needed" bath on accident and am now running laggy/instant shutdown if power cable unplugs. I don't have num pad anyways so no bigy there especially since makers were clever enough to allow standard qwerty to do all needed actions. Current character going on day 10 soon. This game is so epic cracks me up at every turn. Right now I am spending my time rollerblading around town with 20 throwing knives, a caltrop, kukari, and an 870 shotgun for emergencies. With 42 base move cost(on flat tiles) and lvl 9 throwing, kiting zombies is laugh riot, even with (or maybe especially with) shopping carts in tow.
Big thanks to everyone for helping me get setup, I never realized how ridiculously easy Wine is.